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  07/30/2020

  Christopher Viveiros Oral History, 2020/07/30

  Northeastern University student Alex Bice interviewed the Director of Communications at Fenway Health Christopher Viveiros. In this interview, they discuss what Fenway Health does for its community and how the COVID-19 pandemic has affected their interactions with the community. Fenway Health has been able to create signage, update its website, send out emails, and resort to telehealth appointments to help the people in the community that doesn’t to be seen in person. Viveiros is concerned that the voices of many minority communities are not being heard, but is glad that some health officials have been able to speak the truth.
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  2020-07-14

  Moderna Phase 1 results show coronavirus vaccine safe, induces immune response

  Moderna Inc’s experimental vaccine for COVID-19 showed it was safe and provoked immune responses in all 45 healthy volunteers in an ongoing early-stage study, U.S. researchers reported on Tuesday. Volunteers who got two doses of the vaccine had high levels of virus-killing antibodies that exceeded the average levels seen in people who had recovered from COVID-19, the team reported in the New England Journal of Medicine. No study volunteers experienced a serious side effect, but more than half reported mild or moderate reactions such as fatigue, headache, chills, muscle aches or pain at the injection site. These were more likely to occur after the second dose and in people who got the highest dose. Experts say a vaccine is needed to put an end to the coronavirus pandemic that has sickened millions and caused nearly 575,000 deaths worldwide. Moderna was the first to start human testing of a vaccine for the novel coronavirus on March 16, 66 days after the genetic sequence of the virus was released. Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases, whose researchers developed Moderna’s vaccine candidate, called the results “good news,” noting that the study found no serious adverse events and the vaccine produced “reasonably high” levels of virus-killing or neutralizing antibodies. “If your vaccine can induce a response comparable with natural infection, that’s a winner,” Fauci said in a telephone interview. “That’s why we’re very pleased by the results.” Moderna shares jumped more than 15% in after-hours trading on Tuesday. The U.S. government is supporting Moderna’s vaccine with nearly half a billion dollars and has chosen it as one of the first to enter large-scale human trials. A successful vaccine could be a turning point for Cambridge, Massachusetts-based Moderna, which has never had a licensed product. Moderna’s shot, mRNA-1273, uses ribonucleic acid (RNA) - a chemical messenger that contains instructions for making proteins. When injected into people, the vaccine instructs cells to make proteins that mimic the outer surface of the coronavirus, which the body recognizes as a foreign invader, and mounts an immune response against. The results released Tuesday involved three doses of the vaccine, tested in groups of 15 volunteers aged 18-55 who got two shots, 28 days apart. The groups tested 25, 100 or 250 micrograms of the vaccine. Adverse events after the second dose occurred in seven of the 13 volunteers who got the 25-microgram dose, all 15 participants who received the 100 microgram dose and all 14 who got the 250 microgram dose. In the highest-dose group, three patients had severe reactions such as fever, chills, headache or nausea. One of these had a fever of 103.28 Fahrenheit (39.6 C). “We didn’t see any events that are characterized as serious adverse events,” said lead author Dr Lisa Jackson of Kaiser Permanente Washington Health Research Institute in Seattle, referring to reactions that require hospitalization or result in death. In June, Moderna said it selected the 100-microgram dose for its late-stage study to minimize adverse reactions. At that dose, Moderna said the company is on track to deliver about 500 million doses per year, and possibly up to 1 billion doses per year, starting in 2021, from the company’s internal U.S. manufacturing site and strategic collaboration with Swiss drugmaker Lonza. “It’s a good first step,” said Dr William Schaffner, a vaccine expert at Vanderbilt University Medical Center who was not involved in the study. “There’s nothing here that would inhibit one from going ahead to the Phase 2/Phase 3 trials,” he said. In April, Moderna expanded the Phase 1 trial to include adults over 55, who are more at risk of serious disease, with the aim of enrolling 120 volunteers. Moderna said it will follow study volunteers for a year to look for side effects and check how long immunity lasts. Moderna started its phase 2 trial in May and expects to start a phase 3 trial on July 27. Phase 1 trials aim to ensure a treatment is safe and help determine an effective dose. Phase 2 trials test a treatment in a larger group and get an early read on effectiveness. Phase 3 trials are conducted in a large group of individuals to confirm efficacy and identify rare side effects. Moderna’s Phase 3 trial will be conducted in 30,000 volunteers.
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  2020-07-14

  What Happens When A Pandemic And An Epidemic Collide

  From the article: "The ability of the world to mobilize quickly in the fight against COVID-19 owes a lot to the groundwork laid in the fight against HIV, said Dr. Deborah Birx, U.S. Global AIDS Coordinator and U.S. Special Representative for Global Health Diplomacy. She is a member of the White House's coronavirus task force. 'It's the platforms that we've built together and the relationships that are going to be our solutions not only for HIV but our response to COVID-19 around the world,' she said in remarks at the virtual AIDS conference."
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  2020-06-13

  Dr. Anthony Fauci Gives Graduation Address to UC Irvine

  Dr. Anthony Fauci was the country's medical leader in the COVID-19 time. He stood by President Trump's side at the daily Coronavirus briefings and, along with Dr. Deborah Birx, alternately reassured the country and alarmed them. They were often shamed by Trump who tended to make light of the danger of the virus. They were the heroes that stood strong and displayed real leadership and knowledge. Since almost all graduation ceremonies were canceled for spring 2020, various VIPs tried to compensate by giving commencement addresses. Here is Dr. Fauci's.
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  2020-04-26

  How the coronavirus has impacted the U.S. military

  This article in-depthly goes over the current pandemic and how it is specifically affecting the U.S. military.